What is ANTALVISC® ?
ANTALVISC® is a single injection medical device indicated for the prevention and treatment of osteoarthritis (OA). It is injected in joints to relieve pain, restore articular function and protect cartilage.
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is made of non-animal, high molecular weight, cross-linked hyaluronic acid and mannitol. Hyaluronic acid (HA) is a molecule that occurs naturally in the body, especially in cartilage and synovial fluid. HA provides the lubrication and cushioning in a normal joint.
Mannitol, a natural sugar alcohol, is a strong antioxidant and free radical scavenger that protects HA from chemical degradation and rapid depolymerisation.
The intraarticular injection of HA, called viscosupplementation, is commonly used in clinical practice for the management of OA. Its effectiveness has been demonstrated by extensive clinical trials, and it is recommended by different scientific advisory bodies like EULAR (European League Against Rheumatism), OARSI (Osteoarthritis Research Society International), ACR (American College of Rheumatology) and APS (American Pain Society).