Osteoarthritis (OA) is the most common joint disorder and a leading cause of chronic disability. Its prevalence increases with age and the common symptoms are pain, stiffness and loss of motion. OA most often affects knees, hips, spine, hands and feet, but can affect almost any joint in the body.
Osteoarthritis is the result of mechanical and biological events that destabilize the balance between synthesis and degradation of cartilage and which affects all articular structures.
In OA joints, the molecular weight and concentration of HA are diminished. As a result, the synovial fluid has lower viscosity and elasticity, decreasing its ability to lubricate the joint and absorb shocks. The articular surfaces are therefore altered and the cartilage degraded by the forces of friction and compression, leading to significant pain and function loss.
OA is a chronic condition that gradually worsens over time and can become rapidly painful and incapacitating. ANTALVISC® may prevent and slow its progression and reduce joint pain and stiffness.